Neuropsychiatric Complications of COVID-19

The neuropsychiatric complications of COVID-19 have emerged as significant concerns, reflecting the virus's impact beyond respiratory symptoms. Patients may experience a range of neurological and psychiatric symptoms, including delirium, encephalopathy, stroke, and acute disseminated encephalomyelitis . Long COVID, characterized by persistent symptoms after acute infection, often includes cognitive deficits, fatigue, mood disturbances, and anxiety. COVID-19's neurological effects are linked to direct viral invasion, neuroinflammation, and immune responses triggering autoimmune reactions affecting the nervous system. Psychiatric complications such as depression, anxiety disorders, and post-traumatic stress disorder  are heightened by the pandemic's stressors, isolation, and bereavement. Neuroimaging and biomarker studies reveal structural and functional brain changes in COVID-19 patients, underscoring the virus's neurotropic potential. Treatment involves multidisciplinary approaches integrating neurology, psychiatry, and rehabilitation to manage symptoms and support recovery. Long-term implications and the impact on mental health systems globally are subjects of ongoing research and concern. Understanding these complications is crucial for developing effective therapies and support strategies for individuals affected by COVID-19's neuropsychiatric sequelae.

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